P0300 on Ram vehicles Misfire detected, but not isolated to one cylinder

A model year is listed because the code is named in its own record — a bulletin filed against it, or an owner’s complaint about it — not because every one of these vehicles sets it. Counts are documents in NHTSA’s files, not failure rates.

Bulletins and campaigns Ram filed with NHTSA whose summary names P0300. Quote the document number at the service desk — it is a diagnosis the maker has already written down.

• 18-071-24 Service bulletin
  2024-09-21 · Power Train
• "Flash: Powertrain Control Module (PCM) Updates Customers must experience a Malfunction Indicator Lamp (MIL) illumination and the vehicle must exhibit/set one or more of the following Diagnostic Trouble Codes (DTCs): ● P018B - Fuel Pressure Sensor ""B"" Circuit Range/performance. ● P2AF6 - Starter Relay 3 Stuck Off. ● P1CEA - Boost Side EVAP Purge System Performance. ● U0104 - Lost Communication W
• 18-071-24 REV. A Service bulletin
  2024-10-08 · Power Train
• "Flash: Powertrain Control Module (PCM) Updates Customers must experience a Malfunction Indicator Lamp (MIL) illumination and the vehicle must exhibit/set one or more of the following Diagnostic Trouble Codes (DTCs): ● P018B - Fuel Pressure Sensor ""B"" Circuit Range/performance. ● P2AF6 - Starter Relay 3 Stuck Off. ● P1CEA - Boost Side EVAP Purge System Performance. ● U0104 - Lost Communication W
• 18-071-24 REV. B Service bulletin
  2024-11-01 · Power Train
• "Flash: Powertrain Control Module (PCM) Updates Customers must experience a Malfunction Indicator Lamp (MIL) illumination and the vehicle must exhibit/set one or more of the following Diagnostic Trouble Codes (DTCs): ● **P0325 - Knock/Combustion Vibration Sensor 1 Circuit. ● P0330 - Knock/Combustion Vibration Sensor 2 Circuit. ● P032A - Knock-Combustion Vibration Sensor C Circuit.** ● P018B - Fuel
• 18-062-20 REV. A Service bulletin
  2020-12-16 · Electrical System
• Flash: Powertrain Control Module (PCM) Updates This bulletin involves reprogramming the PCM with the latest available software. Customers may experience a Malfunction Indicator Lamp (MIL) illumination. Upon further investigation the technician may find that the one or more of the following DTCs have been set:P0300 - Multiple Cylinder Misfire. P0301 - Cylinder 1 Misfire. P0302 - Cylinder 2 Misfir
• 18-022-21 Service bulletin
  2021-02-17 · Power Train
• Flash: Powertrain Control Module (PCM) Updates This bulletin involves reprogramming the PCM with the latest available software. Customers may experience a Malfunction Indicator Lamp (MIL) illumination. Upon further investigation the technician may find that the one or more of the following DTCs have been set:P0300 - Multiple Cylinder Misfire. P0301 - Cylinder 1 Misfire. P0302 - Cylinder 2 Misfir
• 1802221 Service bulletin
  2021-02-17 · Power Train — Automatic Transmission — Control Module (Tcm/Pcm/Tecm)
• Flash: Powertrain Control Module (PCM) Updates This bulletin involves reprogramming the PCM with the latest available software. Customers may experience a Malfunction Indicator Lamp (MIL) illumination. Upon further investigation the technician may find that the one or more of the following DTCs have been set:P0300 - Multiple Cylinder Misfire. P0301 - Cylinder 1 Misfire. P0302 - Cylinder 2 Misfir
• 1808422 Service bulletin
  2022-04-26 · Back Over Prevention
• Flash: Powertrain Control Module (PCM) Updates This bulletin involves reprogramming the PCM with the latest available software. Customers may experience a Malfunction Indicator Lamp (MIL) illumination. Upon further investigation the technician may find that the one ormore of the following Diagnostic Trouble Codes (DTCs) have been set: P0300 - Multiple Cylinder Misfire. P012A - Turbocharger/Super
• 9100143 Service bulletin
  2023-05-02 · Engine And Engine Cooling — Engine — Crank/Camshaft Position Sensor
• PSU right intake camshaft Case 1) If you are to flash the PSU (Pentastar Upgrade Engine) PCM due to P0300 code presence, only AB or previous LEVEL PSU right intake camshaft PN 05047913AA or AB (old version) should be replaced. If the engine is equipped with the AC/AD LEVEL PSU right intake camshaft PN 05047913AC or AD (new version), camshaft should NOT be replaced. Case 2) If the intake camshaft
• 18-046-24 Service bulletin
  2024-05-08 · Power Train
• "Flash: Powertrain Control Module (PCM) Updates Customers must experience a Malfunction Indicator Lamp (MIL) illumination and the vehicle must exhibit/set one or more of the following Diagnostic Trouble Codes (DTCs): ● P0300 - Multiple Cylinder Misfire. ● P0301 - Cylinder 1 Misfire. ● P0302 - Cylinder 2 Misfire. ● P0303 - Cylinder 3 Misfire. ● P0304 - Cylinder 4 Misfire. ● P0305 - Cylinder 5 Misfi
• 18-020-25 Service bulletin
  2025-04-17 · Power Train
• "Flash: Powertrain Control Module (PCM) Updates Customers may comment on one or more of the following: ● Malfunction Indicator Lamp (MIL) or check engine light illuminated. ● Cruise control drops out/cancels on its own. ● Engine stumble, runs rough, or a slight lack of power. The following software enhancements are also available: ● Reduce the occurrence of false faults DTCs P0300 and P0315. ● DTC
• 18-020-25 REV. A Service bulletin
  2025-05-15 · Power Train
• "Flash: Powertrain Control Module (PCM) Updates Customers may comment on one or more of the following: ● Malfunction Indicator Lamp (MIL) or check engine light illuminated. ● Cruise control drops out/cancels on its own. ● Engine stumble, runs rough, or a slight lack of power. The following software enhancements are also available: ● Reduce the occurrence of false faults Diagnostic Trouble Codes (D
• 18-020-25 REV. B Service bulletin
  2025-09-30 · Unknown Or Other
• Flash: Powertrain Control Module (PCM) Updates *Customers must experience a Malfunction Indicator Lamp (MIL) illumination and the vehicle must exhibit/set one or more of the following Diagnostic Trouble Codes (DTCs):** ● **P0263 - 00 Cylinder 1 Contribution/balance. ● P0266 - 00 Cylinder 2 Contribution-balance. ● P0269 - 00 Cylinder 3 Contribution/balance. ● P0272 - 00 Cylinder 4 Contribution/bala

A stored code names the test that failed, never the part that caused it. The record above is what Ram and its owners have filed about it; the code’s page across every make has the whole file.